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GLP-1 activation also slows gastric emptying, which means food stays in the stomach longer after eating

This can create inequality in access

However, Contrave is FDA-approved for weight loss which may make it easier to qualify if you do not have depression or are not currently smoking cigarettes

Key secondary endpoints included non-inferiority of tirzepatide (5 mg) compared to insulin degludec in HbA1c reduction, superiority of all tirzepatide doses over insulin degludec in HbA1c reduction and weight loss, and the proportion of participants achieving an HbA1c level below 7.0% at week 52

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10.1038/clpt.1981.154 63 NauckM