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A 2020 study of "wellness" B12 injections in non-deficient adults found no improvement in energy, mood, or cognitive function versus placebo at 4 weeks (Wolffenbuttel et al., Nutrients , 2020)
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In summary, the neurological prognosis of GDH-HI patients depends on multiple factors, including the age of onset, diet control, and compliance to medication
10.1056/NEJM199908123410702 35 EngP
Funding The author declares that no financial support was received for the research, authorship, and/or publication of this article
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