Initially, a person may need B12 supplementation shots every other day for around 2 weeks or until symptoms improve
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Duration is determined by the doctor individually, depending on the severity of the symptoms of the disease, but should not exceed 2 weeks
Compounded preparations are dispensed by a licensed 503A pharmacy pursuant to a prescription based on documented clinical need
In available research it's generally been well-tolerated, but human safety data is limited and it's not FDA-approved which is why it should only be used under medical supervision