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The dual-agonist design was first characterized by Coskun and colleagues, who showed that a single peptide could engage both receptors with carefully tuned affinities (Coskun et al., Molecular Metabolism 2018

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ShimadaKMurayamaTYokodeMKitaTUzuiHUedaTet alN-acetylcysteine reduces the severity of atherosclerosis in apolipoprotein E-deficient mice by reducing superoxide production

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