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An October 2024 survey by PwC of some 3,000 U.S

By the one-year mark, participants in the placebo group had regained approximately 6.9% of body weight about two-thirds of what they'd lost

And then they looked at who was also on hormone replacement therapy, and that was either oral or transdermal estradiol, not vaginal estradiol

Its multifaceted mechanism of action, encompassing weight reduction, metabolic normalization, and marked hepatic fat clearance, underscores its potential role in the further investigation of metabolic liver diseases.

5 days), this doesnt support extending the dosing interval to 14 days, as blood levels would still fall substantially below desired levels