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Diabetes, obesity & metabolism, 28(1), 8393.
A pivotal study published in the New England Journal of Medicine reported that participants who received the highest dose of Zepbound (15 mg) lost an average of 22.5% of their body weight after 72 weeks of treatment
But the protein-first structure and mindset should stay in place
But they also come with tradeoffs: Nausea, GI distress, muscle loss risk Dependency on an external signal No retraining of metabolic behavior They dont fix metabolism
Many patients notice improvements after a series of sessions, with maintenance treatments helping to prolong the results
For the study, researchers randomly assigned roughly 1,700 adults with type 2 diabetes to take one of two doses of the new GLP-1 pill, orforglipron, or one of two doses of oral semaglutide
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