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Our study showed that HepG2 cells, which primarily rely on extracellular cystine as a source of cysteine 20 , responded to cystine deprivation by reducing anabolic signaling including attenuation of mTORC1 pathway and activation of the ISR (Fig

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For the determination of arteriovenous difference, we measure the partial pressure of oxygen in the samples of the flowing in and out solution of the heart using a gas analyzer BMS3Mk2 (Denmark)