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These agents enhance glucose-dependent insulin secretion from pancreatic beta cells, suppress inappropriate glucagon release, slow gastric emptying, and promote satiety through central nervous system pathways

Curcumin , the active compound in turmeric, has been studied for its anti-inflammatory and metabolic effects

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A supplement regimen of 400 g of folic acid, 2 mg of vitamin B 6 , and 6 g of vitamin B 12 has been advocated by the American Heart Association if an initial trial of a folate-rich diet (see Sources) is not successful in adequately lowering homocysteine concentrations (95)