20 Glutamate This naturally occurring amino acid is often forgotten, but it is extremely important as it is the most abundant of all neurotransmitters
Furthermore, the downregulation of major histocompatibility complex class I (MHC-I) molecules impairs antigen presentation, effectively hiding tumor cells from cytotoxic T lymphocytes
Oxidative stress means an imbalance of antioxidants and radicals
doi: 10.1038/s41584-025-01302-0
It also sends signals to the brain to decrease hunger and food consumption making it easier to cut down on calorie intake similar to an appetite suppressant
Biochem Soc Trans 43:621626 Li W, Khor TO, Xu C, Shen G, Jeong W-S, Yu S, Kong A-N (2008) Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis