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People with more fat to lose see faster initial progress
But these levels naturally decline with age and drop even further in response to chronic stress, inadequate sleep, poor dietary protein intake, heavy alcohol use, and prolonged exposure to environmental pollutants
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2021 Dec;53(11):e14234
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These users report appreciating treatment benefits while active but watching improvements gradually fade over months post-discontinuation, with timeline showing first 2 months maintaining most benefits creating initial optimism, months 2-4 showing noticeable decline returning toward baseline, months 4-8 continuing regression approaching pre-treatment status, and stabilization occurring 60-80% back toward original baseline with only modest long-term improvement retention
