Clinical trials have documented constipation rates of approximately 24% with semaglutide 2.4mg (Wegovy) in the STEP trials and 15-20% with liraglutide 3.0mg (Saxenda), though individual experiences vary considerably
The 21% figure deserves context
~8590% liver-fat reduction in Phase 2a MASLD 3 Absent by design ~144 h (~6 days) ~120 h (~5 days) 1 top-line (TRIUMPH-4)
[1] [2] Semaglutide works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, and reduces appetite
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When asked about medications, clearly state that you are taking tirzepatide (or semaglutide) and specify the frequency, dose form, and duration of treatment