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Importantly, inactivation of mSOD1 specifically in NG2 + cells delayed disease onset in mice and increased their survival, suggesting that oligodendrocytes are a potential therapeutic target in ALS [107]

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Int J Mol Med (2014) 34(2):47582.10.3892/ijmm.2014.1787 39 Pacheco-PantojaELRanganathLRGallagherJAWilsonPJFraserWD

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