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Gary Brecka helped me

Vitamin C mechanisms involve serving as enzymatic cofactor for collagen hydroxylation and providing direct antioxidant protection, creating effects requiring ongoing application for maintaining antioxidant benefits but potentially supporting durable collagen improvements if used sufficiently long

In the same way, you want to avoid taking it if you need to be fully alert (like right before a road trip)

Because no official human dosing study exists

Glutathione is made naturally by your body, but unfortunately Glutathione levels reduce with age

There is information that methyl ester of JA (MeJA) affects the pools of stress antioxidant enzymes activity to combat oxidative stress (Jung, 2004)