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Factoring in this time difference, when it comes to ION, the proportional risk was higher with Wegovy than Ozempic, the study authors concluded

FDA intends to take action against non-FDA-approved GLP-1 drugs

Use oral rehydration solutions, stick to bland, small meals until stools normalize, and avoid taking anti-diarrheal agents as a long-term fix without medical advice

When combined with semaglutide, the effects may appear stronger or more noticeable

GLP-1 risks While GLP-1 drugs are generally safe, especially for people with diabetes or obesity, they can cause side effects like nausea or, in some cases, loss of muscle mass, which is a concern for older adults

Time Magazine , Medicare Wont Cover GLP-1 Weight Loss Drugs (Apr 2025) ( [21] )