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[DOI] [PubMed] Yu YC, Mao YM, Chen CW, Chen JJ, Chen J, Cong WM, et al

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(118) demonstrated that NOTCH signaling activation induces transcription of Asb2 and Skp2

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Because the immune system plays an important role in controlling HSV-1 reactivation from the brain, episodes of immune-depression such as concomitant infections or stimuli, such as fever episodes may reactivate HSV-1 from neurons and allow the virus to enter a lytic replication cycle (Sawtell and Thompson, 2016)