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It is a tripeptide, composed of three amino acids: glutamate (glutamic acid), cysteine and glycine
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Chemical stability, gastrointestinal absorption, first-pass metabolism, systemic exposure and pathway support are different concepts
Related reading: elevated SAH and SAH hydrolase and low SAM versus elevated SAH
Covalent or non-covalent inhibitors are again attracting attention, and they target site-specifically a cysteine residue near the active pocket of druggable proteins
