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Toxicology 149:4350 Thomas C, Mackey MM, Diaz AA, Cox DP (2009) Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation

Realistic expectations acknowledge both the potential and limitations of peptide therapy

The Journal of international medical research

This oxidative stress contributes to chronic diseases, including cancer, neurodegenerative conditions, and cardiovascular disease

These effects are mediated by the upregulation of TP53, CASP3 and CASP8 genes and the reduction in BCL-2, NRAS and KRAS genes

The increase in LC3A/B protein levels suggests that RSL3 treatment leads PTC cells to autophagy