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Consequently, we observed that this beneficial effect, after direct injury (permanent ligation) applied to one or two major vessels, could instantly oppose more general damage (maintained intra-abdominal hypertension, either high (grade III) or very high (grade IV)), as all blood vessels which can be compressed with increased intra-abdominal pressure
2 However, GLP-1 receptors are expressed throughout the human body and are not limited to pancreatic and gastrointestinal cell types
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The constipation risk is comparable
However, hypotension (low blood pressure in general) has been documented in a small proportion of patients, particularly in those experiencing significant gastrointestinal side effects leading to dehydration
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