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Un alt rol important este legat de detoxificare la nivel hepatic: glutationul este utilizat in reactii de conjugare (prin enzimele glutathione S-transferase), prin care anumite substante sunt transformate in forme mai usor de eliminat

The RA/RAR signaling pathway protects Treg function and promotes Treg differentiation by increasing Smad3 and Foxp3 expression [70, 71]

The mechanism may involve multiple effects: enhanced autophagy (cellular cleanup), reduced neuroinflammation, improved mitochondrial energy metabolism, and enhanced BDNF signalling

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However, more research is needed to prove how well it works and how safe it is in the long term