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In phase 2 trials of HFpEF, agents that reduce NT-proBNP have been shown to reduce clinical events in large, randomized trials

In contrast, two independent embryos harboring biallelic Trim37 mutations displayed severe PGC loss, fulfilling our predefined screening criteria for a positive hit and identifying Trim37 as a positive candidate gene in this screen (Fig

Now, researchers are exploring new iterations, including oral versions and multi-pathway therapies

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Throughout the study, it was observed that when the peptide was exposed to the murine model, it appeared to quickly clear from the serum and evenly distribute into tissue

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