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Important: compounded medications are not FDA-approved and carry inherent variability in manufacturing compared to branded products

So the pill is mainly an option for people who would rather not inject, rather than a way to reach more weight loss

The SURMOUNT-5 head-to-head trial confirmed tirzepatide produced about 20% weight loss vs

Bottom line: While Canada offers lower retail prices, the risks of customs seizures, shipping temperature failures, and legal ambiguity make US-based telehealth a more reliable and holistic solution for sustainable weight management

However, further research is required confirming these hypotheses

Weight Regain and Cardiometabolic Effects After Withdrawal of Semaglutide: The STEP 1 Trial Extension Diabetes, Obesity and Metabolism 24(8) 2022PMID: 35441470 PubMed 4 Drucker DJ Mechanisms of Action and Therapeutic Application of Glucagon-like Peptide-1 Cell Metabolism 27(4) 2018PMID: 29617641 PubMed 5 van Bloemendaal L, IJzerman RG, ten Kulve JS, et al