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It typically peaks during the first one to two weeks at each new dose level and gradually diminishes as the body adapts

The role of neuroinflammation in depression is well-established, with elevated levels of pro-inflammatory cytokines and reduced levels of anti-inflammatory cytokines being associated with depressive symptoms 20

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Expression levels of insulin, TGF-1, -SMA, and collagen I were normalized to that of -actin and expressed relative to that in the sham group [22]

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