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If atherosclerotic CV disease or chronic kidney disease are not present, the priorities are weight reduction (or prevention of weight gain) and avoidance of hypoglycaemia

What to Expect: A Realistic Timeline for Shed GLP-1 Week 1 to 2: Most members notice appetite changes within the first week

Short-term GLP-1 receptor agonist exenatide ameliorates intramyocellular lipid deposition without weight loss in ob/ob mice

It appears to be safe in ongoing studies, but long-term effects are still being researched

Other patients may work with their providers to lower their dose or discontinue the medication altogether once their weight loss goals are achieved and a healthy lifestyle foundation is established

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