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Ectopic expression of SARS-CoV-2 S and ORF-9B proteins alters metabolic profiles and impairs contractile function in cardiomyocytes
Highlighting the potential of this approach, several recent translational and clinical studies beyond the field of MS used this method of delivery and were able to clear intracellular tau pathology in tauopathy mice by intranasal application of an anti-tau-antibody (144) or reduce apathy in frontotemporal dementia patients by intranasal application of oxytocin (149) ( Figure 2C )
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Published literature may describe AOD9604 in controlled experimental settings
As a peptide, BPC-157 also carries a theoretical potential for immunogenicity (antibody formation) with repeated dosing, which has not been studied longitudinally in dogs
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