When NNMT activity is elevated as documented in obese adipose tissue, several cancer types, and aged skeletal muscle intracellular NAD+ availability decreases, SAM availability decreases, and downstream sirtuin activity (particularly SIRT1 and SIRT3) is reduced
The peptides can be designed for transcription factors, specific receptors, and tumor suppressor proteins to disrupt the regulation of timing/rate of gene expression and cell cycle progression
A faster metabolism can help your body burn calories more efficiently
It also significantly improved cardiometabolic parameters, including blood pressure, HbA1c, lipids, and C-reactive protein
They provide modest short-term relief but lose effectiveness over time as tolerance builds
Cite as: Elgar, K