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Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover
It originates from the preproglucagon precursor, which undergoes enzymatic processing within intestinal L-cells, ultimately giving rise to GLP-1(1-37) and GLP-1(7-36) amide or GLP-1(7-37) peptide variants
Lai ZW, Hanczko R, Bonilla E, et al
Using process tracing, we investigate the mechanisms driving differences in policy outcomes and effectiveness
Human results are not established, and large human trials have not been completed, which is a critical limit to keep in mind
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