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These studies report a significant reduction in tumour burden upon the systemic depletion of cysteine using cyst(e)inase
The two arms were reasonably well balanced with respect to the presence of cardiovascular comorbidities (angina, valvular disease, congestive heart failure, hypertension, diabetes, hyperlipidemia, and cardiac revascularization), with the placebo arm having marginally higher rates of cardiac arrhythmia (19% vs 11%), myocardial infarction (MI) (39% vs 30%), and obesity (BMI 30 kg/m 2 78% vs 66%)
doi: 10.3389/fendo.2022.882998 Received 24 February 2022 Accepted 21 September 2022 Published 10 October 2022 Volume 13 - 2022 Edited by ke Sjholm, Gvle Hospital, Sweden Reviewed by Zhanna Belaya, Endocrinology Research Center, Russia