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Considering the pivotal function of ferroptosis in OA, targets such as transient receptor potential vanilloid 1 (TRPV1) [27,28], glutathione peroxidase 4 (GPX4) [29], nuclear factor erythroid 2-related factor 2 (NRF2) [30], acyl-CoA synthetase long-chain family member 4 (ACSL4) [31], and nuclear coactivator adaptor 4 (NCOA4) [32] have surfaced as prospective regulators of ferroptosis and modulators of OA advancement

Vitamin C plays a direct role in collagen formation

Medical professionals and researchers will find comprehensive analysis of the peptide's cellular pathways, pharmacokinetic properties, and translational considerations for clinical practice

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MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism

Pathogen recognition receptors: ligands and signaling pathways by toll-like receptors