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Here is a refined table displaying examples of common off-label drug use: Legal Aspects of Off-Label Prescriptions Off-label drug prescriptions are entirely legal in the U.S., as the FDA focuses on approving medications for their initial intended uses but does not regulate or prohibit off-label prescribing

Metabolism abnormalities induced by exposure to excessive UA are important factors mediating the pathological development of HUA-associated multiple organ complications (Bergamini et al., 2009

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