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Journal of Alternative and Complementary Medicine

They conducted an in-vivo (made on real people) study with 33 participants and found that the test formula, with just 0.5% AAP, "significantly" reduced hyperpigmentation (age spots) after 8 weeks (by 29-33%)

Pentadecapeptide BPC-157: from GI tract to whole body healing Related research, protocols, and guides Explore the available research context, protocol variants or comparisons, and practical guides

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Additionally, rectal administration can result in higher bioavailability and faster onset of action compared to some other routes, as the medication bypasses the first-pass metabolism in the liver