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Power: Each tablet contains Semaglutide 14 mg as the active ingredient
What Clinical Trials Show In large obesity trials: Average weight loss is ~15% of starting body weight with semaglutide 2.4 mg Average weight loss is ~2022% of starting body weight with tirzepatide 15 mg The majority of weight loss occurs within the first year of treatment Plateaus are common after significant weight reduction Some people lose more, some less but a flattening of the weight-loss curve is expected , especially after meaningful progress has already occurred
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What a Responsible Clinical Conversation Looks Like A responsible reading of this paper sounds like this: nabiximols, already used for MS spasticity, shows a plausible pooled signal of broader benefit across bladder function, sleep, spasm quality, and gait, and that signal is worth discussing with patients who are already candidates for the medicine or already using it
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