Gynecol Endocrinol 34:684688
A post-mortem study of human pancreases demonstrated proliferative effects in those cases with GLP-1RA use, which were manifest by an increased mass of the pancreas along with increased frequency of PanIN1 and PanIN2 lesions compared to diabetes controls 23
Mitochondria are also involved in key cellular functions such as Ca 2 + homeostasis, heme biosynthesis, nutrient metabolism (Renault and Chipuk, 2013)
In this podcast episode, McCall McPherson explores the complexities of Graves' disease and hypothyroidism
The loss of HNF1A and FXYD2 may induce membrane hyperpolarization, thereby impairing insulin secretiona mechanism relevant to both maturity-onset diabetes of the young type 3 (MODY3) and T2D (Weng et al., 2023)
According to prescribing information, they may be contraindicated in certain situations