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The primary goal of PIONEER 6 was to compare the time to the first major adverse cardiovascular event between oral semaglutide and placebo

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doi: 10.1016/j.devcel.2012.10.019 60 DaiNRapleyJAngelMYanikMFBlowerMDAvruchJ

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While its unclear which, if any, of the rich and famous are actually taking the drug, billionaire Elon Musk was quick to respond to questions on Twitter about his newly ripped physique by crediting fasting before adding, and Wegovy. The prescription medications, sold under brand name Wegovy for weight loss, and Ozempic for diabetes (and prescribed off-label for weight loss), have made their way into the mainstream thanks in part to Reddit threads and social media