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Milazzo, L., Menzaghi, B., Caramma, I., Nasi, M., Sangaletti, O., Cesari, M., Zanone, Poma B., Cossarizza, A., Antinori, S., and Galli, M

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Pickart's foundational work and subsequent studies on copper peptides and wound closure point to upregulation of matrix metalloproteinases, the enzymes responsible for remodeling collagen into organized structure during repair, rather than the disorganized collagen deposition that produces visible scarring

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Look for these signs: Covering ears or eyes frequently Escaping or withdrawing from busy environments Irritability, crying, or emotional outbursts Clumsiness or uncoordinated movement Repetitive behaviors like rocking, pacing, or hand-flapping Trouble focusing or shutting down in stimulating settings If these behaviors appear frequently, it may be helpful to introduce sensory breaks during high-demand parts of the day, like transitions or after school