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Cellular lipid ROS assay Lipid ROS levels were measured through oxidation of the C11-Bodipy lipid peroxidation sensor (Thermo Fisher Scientific) according to the manufacturers instructions
This calculation also accounts only for steric considerations, while intramolecular and intermolecular interactions, such as chargecharge repulsion, can result in larger effective molecular volumes
In diet-induced obese (DIO) mouse models, NNMT inhibition led to approximately 35% reduction in white adipose tissue mass compared to controls
PubMed laboratory research record [PMID: 8207892] PubMed record related to this compound for laboratory literature review
Drug Stability: ICH versus Accelerated Predictive Stability Studies
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