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Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments
NMN (nicotinamida mononucletido) y NR (ribsido de nicotinamida) son precursores que aportan sustrato para que la clula fabrique NAD+
ChenSWeiCGaoPKongHJiaZHuCet al
Cooper BA, Rosenblatt DS
This multi-faceted mechanism makes it a powerful tool for investigating complex metabolic pathways
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