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Geniposide improves repeated restraint stress-induced depression-like behavior in mice by ameliorating neuronal apoptosis via regulating GLP-1R/AKT signaling pathway

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The side effect profiles are very different because their mechanisms are different

Its postulated that its antimelanogenic properties result from a variety of mechanisms including stimulation of pheomelanin synthesis rather than darker eumelanin, its antioxidant effects, and interference with intracellular trafficking of melanin-causing enzymes

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191 This effect was less pronounced in healthy non-obese women with a decrease of insulin release from 108 to 49.3 nmol min/l ( P =0.05)