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Colluci and colleagues [150] used an in vitro model to suggest that carnitine supplementation in the elderly may stimulate osteoblast activity and decrease age-related bone loss

Bruls YM, de Ligt M, Lindeboom L, Phielix E, Havekes B, Schaart G, Kornips E, Wildberger JE, Hesselink MK, Muoio D, Schrauwen P, Schrauwen-Hinderling VB (2020) Mitochondrial dysfunction: a potential therapeutic target to treat Alzheimers Disease

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The picture remains incomplete, however, when assessing the mechanism by which this is achieved and if these cardiovascular effects can be generalized for the entire class of drugs

41 In a meta-analysis of nine RCTs involving 8,920 patients with HF and coexisting T2D, GLP-1 RAs did not improve LVEF, LV end-diastolic volume or LV end-systolic volume

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