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Acknowledgements This research was supported by the National Key R&D Program of China (2018YFC1313304, 2018YFC1313300), National Natural Science Foundation of China (81930065, 81871951), Natural Science Foundation of Guangdong Province (2019A1515010233, 2018B030306049), Pearl River S&T Nova Program of Guangzhou (201806010002), and CAMS Innovation Fund for Medical Sciences (CIFMS) (2019-I2M-5-036)
Loder E et al
This is the first time such technology is being introduced in the skincare industry
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Second, the tissue-specific differences in FA metabolism, where FA metabolism in various organs, such as the liver and kidneys, influences distinct stages of GA progression, and the varying tissue affinities exhibited by drugs, such as the PPAR agonists pioglitazone (113) and aleglitazar (240), exhibit stronger affinity for the hepatic tissue, redistributing visceral fat to peripheral tissues
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