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You may also like Product Description DSIP Peptide | Buy DSIP UK | Research Use Only DSIP Delta Sleep-Inducing Peptide is a naturally occurring amphiphilic nonapeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu, MW 849 Da) first isolated from rabbit cerebral venous blood in 1977 by the Schoenenberger-Monnier group at the University of Basel, found in both free and bound forms in the hypothalamus, limbic system, pituitary, gut, pancreas, and body fluids, that in pre-clinical and limited clinical research demonstrates a uniquely broad neuromodulatory profile promoting delta-wave slow-wave sleep (SWS), modulating corticotropin and GH release, exerting stress-protective and adaptogenic activity, reducing mitochondrial oxidative stress under hypoxia, demonstrating anticonvulsant and antinociceptive activity, accelerating motor research applications post-stroke, and exhibiting geroprotective and anticarcinogenic properties in long-term murine studies making it one of the most pharmacologically diverse endogenous regulatory neuropeptides in the sleep and stress research literature, despite its receptor remaining formally unidentified

Cardiovascular and neurovascular injury: Protection in heart ischemia models, eye injuries, and various CNS insults through combined vascular, antiinflammatory, and antioxidative mechanisms

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LPS-induced sickness behavior in mice shows that the role of BDNF in the response to neuroinflammatory challenge occurs in a sex-dependent manner [280]