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About the ATTAIN-2 Trial Design : Phase 3, 72-week, randomized, double-blind, placebo-controlled
As a downstream target of Nrf-2, oxygenase-1 (HO-1) represents one of the most crucial cellular adaptation mechanisms to oxidative stress
Reduced glutathione reflects both antioxidant capacity and the functional performance of key metabolic pathways involved in sulfur metabolism and methylation balance
Research context The two components have been studied separately in cell and animal models
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