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They are not approved by the TGA, FDA, or any other regulatory body, and are not drugs, medicines, food supplements, cosmetics, or veterinary products

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10.1194/jlr.TR120000972 Ramachandra Rao S, Fliesler SJ: Cholesterol homeostasis in the vertebrate retina: biology and pathobiology

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Over time, toxins build up in the body, leading to physical and psychological dependence, which necessitates detoxification