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R., & Chasman, D

[1] Because intrinsic-factor-dependent uptake in the distal ileum can be absent in conditions such as autoimmune gastritis, pancreatic insufficiency, or bariatric surgery, the intramuscular or subcutaneous route bypasses gastrointestinal barriers and reliably restores serum concentrations

It is worth noting that there is no established link between standard-dose vitamin B12 supplementation and serious gastrointestinal pathology

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