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10.1016/j.pharep.2019.04.004 42 KanehisaM.SatoY.KawashimaM.FurumichiM.TanabeM
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These receptors play important roles in mitochondrial function, energy metabolism, cellular respiration, and metabolic adaptation
Think of it as a direct delivery route
By modifying the primary sequence of OXM and linking to the constant region of human IgG4, Jung and colleagues demonstrated their peptide HM12525A had a potent and balanced activity at both GLP-1 and glucagon receptors in vitro and led to body weight loss of 30% in DIO mice over 14 days compared to liraglutide treated mice (74)
Contraindications Minoxidil contraindications include hypersensitivity to the drug or vehicle ingredients, pregnancy, breastfeeding, and age under 18
