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While consuming this energy, it creates a high amount of reactive oxygen molecules

However, in the non-senescent control fibroblast model cultured in 10% FBS DMEM treated with or without FOXO4-DRI (25 M), no SA--gal-positive cells were observed both in keloid fibroblasts and in normal skin fibroblasts (Supplementary Fig

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In contrast, a slightly delayed and less efficient host response allows limited virus replication and movement first resulting in oxidative stress and programmed cell death before conferring a final arrest of virus invasion (HR) (Bendahmane et al., 2016)