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This means that GLP-1 receptor agonists can limit and stabilize the development of atherosclerotic plaques through anti-inflammatory mechanisms and by preventing vascular remodeling, which ultimately can provide protective effects against major adverse cardiac events (MACEs)

The Cleveland Clinic notes that tolerance is individual, and some high-fiber or gas-producing foods can worsen GI symptoms on GLP-1s, especially during dose escalation, including foods like beans, cruciferous vegetables, and certain starchy produce

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Frontiers in Chemistry, 11

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Glucagon-Like Peptide-1 Receptor Agonists (GLP-1 RAs), a class of glucose-lowering drugs, have demonstrated a wide range of pleiotropic effects that extend beyond glycaemic control