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Similarly, glucoraphanin-rich broccoli (400 g/week) consumed over a 12-week period was found to significantly reduce plasma LDL-C compared to consumption of standard broccoli in two randomized, double-blind parallel studies including 130 adults aged 50 years at risk of cardiovascular disease ( Neurological and Psychiatric Disorders Preclinical evidence suggests that glucosinolates and their metabolites, particularly sulforaphane, exhibit several biological properties that may be relevant to neurological and psychiatric conditions (Wu et al., 2016
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95% CI, 0.58-0.72)
Mechanistically, GLP-1R activation alleviates OA by fostering chondrocyte anabolic metabolism while inhibiting catabolism, safeguarding chondrocytes from endoplasmic reticulum stress and apoptosis, and displaying anti-inflammatory and antioxidant properties [15,16,17]
High oxidative stress levels have been linked to cardiovascular disease, cancer, inflammatory diseases, cataracts, and neurodegenerative disorders (Zakeri et al., 2021)
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