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10.1016/j.toxicon.2018.10.149 32 JingyuanH.YanL.WenjingP.WenqiangJ.BoL.LinghongM.et al (2020)
For more on this, see our visual guide to portion control on GLP-1
As a part of this study, MRI brain scans of all patients were performed at baseline and after 12 months treatment with liraglutide or matching placebo along with neuropsychometric evaluation and [18F]FDG PET
This led Pfizer to focus on the development of a once-daily version of the drug, which showed early success in Phase I trials (NCT06567327 and NCT06568731)
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TolhurstGHeffronHLamYSParkerHEHabibAMDiakogiannakiEet al
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