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Your healthcare provider can assess whether dose adjustments or alternative medications might be appropriate

Endothelial Nitric Oxide Production

Novo Nordisk, the manufacturer of Wegovy, offers a 7.2 mg dose to patients who do not benefit enough from the previous maximum dose of 2.4 mg

Patients receiving sitagliptin with metformin immediate-release and insulin had significant improvements in A1C, FPG and 2-hour PPG compared to patients receiving placebo with metformin immediate-release and insulin (Table 13)

The only side effect Ive experienced is a bit of constipation, but I manage that easily with over-the-counter senna

Consider the risk of abuse before prescribing and monitoring for signs of misuse and addiction