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13 Beyond its canonical actions, GLP-1 exerts pleiotropic effects across multiple organ systems (Figure 1), including the central nervous system, kidney, liver, heart, and immune system, through direct mechanisms linked to binding to its cognate receptors, and via indirect mechanisms secondary to interorgan or intertissue crosstalk

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Research Focus Areas: Growth hormone deficiencies Anti-aging models Fat metabolism Muscle regeneration Legality: Legal for research

found that these two vectors were highly expressed in myocardial mitochondria and showed that inhibition of DIC and OGC increased mitochondrial ROS and GSH depletion, exacerbating ferroptosis in the myocardium [60]